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Article

Licensing microgels prolong the immunomodulatory phenotype of mesenchymal stromal cells.

Frontiers in immunology - 1 Jan 2022

Patrick Matthew D, Annamalai Ramkumar T

Abstract excerpt

Mesenchymal stromal cells (MSC) are sensors of inflammation, and they exert immunomodulatory properties through the secretion of cytokines and exosomes and direct cell-cell interactions. MSC are routinely used in clinical trials and effectively resolve inflammatory conditions. Nevertheless, inconsistent clinical outcomes necessitate the need for more robust therapeutic phenotypes. The immunomodulatory properties...

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PMID: 36059508
DOI: 10.3389/fimmu.2022.987032
PMCID: PMC9433901

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