Article

Calcitonin gene-related peptide and intermedin induce phosphorylation of p44/42 MAPK in primary human lymphatic endothelial cells in vitro

2024-05-14

Abstract excerpt

<h4>Background: </h4> Calcitonin gene-related peptide (CGRP) is a 37-amino acid peptide that belongs to the calcitonin family of peptides together with adrenomedullin (AM), adrenomedullin 2 (AM2), also known as intermedin (IMD), amylin (AMY) and calcitonin. Recent reports demonstrated the efficacy of drugs targeting the CGRP signalling axis for the treatment of migraine, but also revealed significant side effects...

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Literature Corpus work: 723cc65c-7a51-5012-b2c2-64f0c4d67162
DOI: 10.1101/2024.05.11.593644

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