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The Role of Microglia in Neurodevelopmental Disorders and their Therapeutics

21 Feb 2020

Abstract excerpt

The development of new therapeutics is critically dependent on an understanding of the molecular pathways, the disruption of which results in neurological symptoms. Genetic and biomarker studies have highlighted immune signalling as a pathway that is impaired in patients with neurodevelopmental disorders (NDDs), and several studies on animal models of aberrant neurodevelopment have implicated microglia, the...

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PMID: 32091337
DOI: 10.2174/1568026620666200221172619

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