Article

Optimization of An O2-Balanced Bioartificial Pancreas for Type 1 Diabetes Using Statistical Design of Experiment.

2021-06-16

Abstract excerpt

A bioArtificial pancreas (BAP) encapsulating high pancreatic islets concentration is a promising alternative for type 1 diabetes. However, the main limitation of this approach is O 2 supply, especially until graft neovascularization. Here, we described a methodology to design an optimal O 2 -balanced BAP using statistical design of experiment (DoE). A full factorial DoE was first performed to screen two O 2 -techn...

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Literature Corpus work: 721283b6-e933-5c40-be68-ec5d3a34c2a6
DOI: 10.21203/rs.3.rs-600404/v1

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