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Genetic polymorphisms and tumoral mutational profile over survival in advanced colorectal cancer patients: an exploratory study

2023-07-14

Abstract excerpt

Colorectal cancer is a common disease, both in Chile and worldwide. The most widely used chemotherapy schemes are based on 5-fluorouracil (5FU) as the foundational drug. Genetic polymorphisms have emerged as potential predictive biomarkers of response to chemotherapy, but conclusive evidence is lacking. Additionally, the interplay between hereditary variations and acquired mutations in the EGFR pathway remains unk...

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Literature Corpus work
71fbfd19-2515-5b82-95d8-06ddcbceb26c
DOI
10.20944/preprints202307.0972.v1
Open publication

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Genetic polymorphisms and tumoral mutational profile over survival in advanced colorectal cancer patients: an exploratory studyDOI 10.20944/preprints202307.0972.v1
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