Article
Pharmacogenetics of Anticancer Drug Sensitivity and Toxicity in Colorectal Cancer.
Current pharmaceutical design - 1 Jan 2018
Moradi-Marjaneh Reyhaneh, Khazaei Majid, Seifi Sima, Hassanian Seyed Mahdi, Ferns Gordon A, Avan Amir
Abstract excerpt
Inter-individual differences in drug response are an important cause of failure in anticancer treatment and adverse drug events in cancer patients. Gene polymorphisms related to these outcomes have been investigated in an effort to find new genetic biomarkers to predict toxicity and response to anticancer drugs. Evaluating the value single nucleotide polymorphisms (SNPs) in the genes involved in transportation,...
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