Article

Efficient mixed model approach for large-scale genome-wide association studies of ordinal categorical phenotypes

2020-10-10

Abstract excerpt

In genome-wide association studies (GWAS), ordinal categorical phenotypes are widely used to measure human behaviors, satisfaction, and preferences. However, due to the lack of analysis tools, methods designed for binary and quantitative traits have often been used inappropriately to analyze categorical phenotypes, which produces inflated type I error rates or is less powerful. To accurately model the dependence o...

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Literature Corpus work: 3a26d6b9-e2c8-517e-ad1e-6f0e6f191f94
DOI: 10.1101/2020.10.09.333146

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