Article

Glutathione S-Transferase Genotype polymorphism and Primary Open-Angle Glaucoma in an Italian population

2018-09-10

Abstract excerpt

<h4>Purpose</h4> Oxidative damage to the trabecular meshwork (TM) represents one of the pathogenic mechanisms leading to primary open angle glaucoma (POAG). Glutathione S-transferase mu 1 (GSTM1) may neutralizes reactive oxygen species protecting the TM. The present paper investigates the prevalence of GSTM1 null genotype in an Italian population, and its association with POAG treated either medically or surgical...

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Literature Corpus work: 71ba51b1-12e6-52d4-9ca4-6d0cca426f15
DOI: 10.1101/413435

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