Article
Glutathione S transferase M1 and T1 genetic polymorphisms are related to the risk of primary open-angle glaucoma: a study in a Turkish population.
The British journal of ophthalmology - 1 Apr 2007
Unal Mustafa, Güven Mehmet, Devranoğlu Kazim, Ozaydin Ahmet, Batar Bahadir, Tamçelik Nevbahar, Görgün Ebru Eroğlu, Uçar Didar, Sarici Ahmet
Abstract excerpt
BACKGROUND: Genetic factors and oxidative damage have been shown to have a role in the development of primary open angle glaucoma (POAG). AIM: To determine the effects of genetic polymorphisms of glutathione S transferase (GST)M1 and GSTT1 on the risk of POAG in a Turkish population. METHODS: Using a multiplex polymerase chain reaction (PCR), GSTM1 and GSTT1 gene polymorphisms were analysed in 144 patients with...
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