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Article

May glutathione S-transferase M1 positive genotype afford protection against primary open-angle glaucoma?

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Apr 2005

Yildirim Ozlem, Ateş Nurcan Aras, Tamer Lülüfer, Oz Ozay, Yilmaz Ayça, Atik Uĝur, Camdeviren Handan

Abstract excerpt

PURPOSE: To find out whether the polymorphism at GSTM1, GSTT1 and GSTP1 loci is associated with increased susceptibility to glaucoma. METHODS: We genotyped 153 primary open angle patients and 159 healthy controls. Genomic DNA from peripheral blood was examined using polymerase chain reaction and defined for the genetic polymorphisms of glutathione S-transferase. RESULTS: The frequency of the GSTM1 null genotype...

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Identifiers

PMID: 15864623
DOI: 10.1007/s00417-004-1013-9

Genes

GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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