Article
Is the GSTM1 null polymorphism a risk factor in primary open angle glaucoma?
Molecular vision - 1 Jan 2011
Rocha Auta Viviane, Talbot Teddy, Magalhães da Silva Thiago, Almeida Maria Clarinda, Menezes Carlos Alberto, Di Pietro Giuliano, Rios-Santos Fabrício
Abstract excerpt
PURPOSE: To investigate the association of glutathione S-transferase (GST) GSTM1, GSTT1, and GSTP1 genes with the risk of primary open angle glaucoma (POAG) and clinical features of the disease. METHODS: We conducted a case-control study that included 87 Brazilian patients with POAG and 85 healthy controls matched for age, ethnicity, and sex, whose blood samples were genotyped for polymorphisms in GST genes using...
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