Article
[Open angle glaucoma: epidemiology, pathogenesis and prevention].
Recenti progressi in medicina - 1 Jan 2006
Izzotti Alberto, Di Marco Barbara, De Flora Silvio, Saccà Sergio
Abstract excerpt
There is growing evidence that reactive oxygen species (ROS) play a key role in the pathogenesis of primary open angle glaucoma (POAG). The occurrence of oxidative DNA damage in trabecular meshwork (TM) has been demonstrated by measuring the increase of 8-hydroxy-2'-deoxyguanosine, the most abund...
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