Article

Haploinsufficiency of the mouse <i>Tshz3</i> gene leads to kidney dysfunction

2021-08-16

Abstract excerpt

Renal tract defects and autism spectrum disorder (ASD) deficits represent the phenotypic core of the 19q12 deletion syndrome caused by the loss of one copy of the TSHZ3 gene. While a proportion of Tshz3 heterozygous ( Tshz3 +/lacZ ) mice display ureteral defects, no kidney defects have been reported in these mice. The purpose of this study was to characterize the expression of Tshz3 in adult kidney as well as...

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Literature Corpus work: 71969fc3-2522-5f3f-8d15-5c31dfee537e
DOI: 10.1101/2021.08.16.456481

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