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Article

Tulp3 deficiency results in ciliopathy phenotypes during zebrafish embryogenesis.

Scientific reports - 12 Sept 2025

Epting Daniel, Devane John, Mertes Ralf, Kayser Séverine, Helmstädter Martin, Metzger Patrick, Boerries Melanie, Bergmann Carsten, Ott Elisabeth

Abstract excerpt

Ciliopathies, caused by defective cilia biogenesis or function, comprise a genetically and clinically diverse group of diseases. Primary cilia play pivotal roles in the regulation of a multitude of signalling pathways during development and tissue homeostasis. Cilia assembly, maintenance and signalling depend on intraflagellar transport (IFT). Tubby-like protein 3 (TULP3) functions as an adapter protein for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40940409
DOI: 10.1038/s41598-025-16584-3
PMCID: PMC12432116

Genes

TULP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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