Article

From drugs to targets: Reverse engineering the virtual screening process on a proteomic scale

2022-10-20

Abstract excerpt

Phenotypic screening is a powerful technique that allowed the discovery of antimicrobials to fight infectious diseases considered deadly less than a century ago. In high throughput phenotypic screening assays, thousands of compounds are tested for their capacity to inhibit microbial growth in-vitro. After an active compound is found, identifying the molecular target is the next step. Knowing the specific target is...

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Literature Corpus work: 719444c2-3ff4-5d5d-af7f-973c76fd9f21
DOI: 10.3389/fddsv.2022.969983

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