Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Strategic Paradigm Shifts in the Antimicrobial Drug Discovery Process of the 21st Century

1 Sept 2007

Abstract excerpt

The numbers of global infections produced by bacterial strains that are resistant to single and multiple antimicrobial drugs are on the rise. Concomitant with this alarming upward trend, there is a clear downward trend in the intent and determination of pharmaceutical companies to develop novel antimicrobials. One of the pressing goals to confront the twenty first century's public health challenges brought about...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Biochemical and Structural Characterization
Share to Microbial Natural Products and Biosynthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17897059
DOI: 10.2174/187152607782110040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Strategic Paradigm Shifts in the Antimicrobial Drug Discovery Process of the 21st CenturyPMID 17897059Read ↗

Overview of antibacterial target selection.Semantic proximity Read ↗

Targeted treatment for bacterial infections: prospects for pathogen-specific antibiotics coupled with rapid diagnosticsSemantic proximity Read ↗

Review: Antibiotic discovery in the age of structural biology - a comprehensive overview with special reference to development of drugs for the treatment of Pseudomonas aeruginosa infection.Semantic proximity Read ↗

A new determination of pan-pathogen antimicrobialsSemantic proximity Read ↗

A New Determination of Pan-Pathogen AntimicrobialsSemantic proximity Read ↗

From Genome to Drugs: New Approaches in Antimicrobial DiscoverySemantic proximity Read ↗

Progress in the Fight Against Multidrug-Resistant Bacteria 2005–2016: Modern Noninferiority Trial Designs Enable Antibiotic Development in Advance of Epidemic Bacterial ResistanceSemantic proximity Read ↗

KOMBAT: Knowledgebase of Microbes’ Battling Agents for TherapeuticsSemantic proximity Read ↗

Mitigating the Impact of Antibacterial Drug Resistance through Host-Directed Therapies: Current Progress, Outlook, and ChallengesSemantic proximity Read ↗

One ring to rule them all: Current trends in combating bacterial resistance to the β‐lactamsSemantic proximity Read ↗

In Silico/In Vitro Strategies Leading to the Discovery of New Nonribosomal Peptide and Polyketide Antibiotics Active against Human PathogensSemantic proximity Read ↗

Bridging the gap between target-based and phenotypic-based drug discovery.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.