Article

Identification of multi-omic pleiotropy factors for peripheral artery disease

2025-07-14

Abstract excerpt

Abstract Background: Peripheral artery disease (PAD) is prevalent and frequently co-occurs with type 2 diabetes (T2D) and coronary artery disease (CAD). Although shared genetic factors may contribute to these comorbidities, few studies have examined pleiotropy at the transcriptomic and proteomic levels. <h4>Methods:</h4> We generated summary statistics for transcriptome-wide (TWAS) and proteome-wide (PWAS) associa...

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Literature Corpus work: 71509062-3d86-557f-b7bc-00c630483073
DOI: 10.1101/2025.07.11.25331391

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