Article

Understanding K. phaffii ( Pichia pastoris ) Host Cell Proteins: Proteomic Analysis and Flow-through Affinity Clearance

2023-02-01

Abstract excerpt

K. phaffii is a versatile expression system that is increasingly utilized to produce biological therapeutics – including enzymes, engineered antibodies, and gene-editing tools – that feature multiple subunits and complex post-translational modifications. Two major roadblocks limit the adoption of K. phaffii in industrial biomanufacturing: its proteome, while known, has not been linked to downstream process operat...

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Literature Corpus work: 71353391-8655-556f-9347-3785a9ea0e44
DOI: 10.22541/au.167525487.74773202/v1

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