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Adaptation of Aglycosylated Monoclonal Antibodies for Improved Production in Komagataella phaffii

2024-07-16

Abstract excerpt

Monoclonal antibodies (mAbs) are a major class of biopharmaceuticals manufactured by well-established processes using Chinese Hamster Ovary (CHO) cells. Next-generation biomanufacturing using alternative hosts like Komagataella phaffii could improve the accessibility of these medicines, address broad societal goals for sustainability, and offer financial advantages for accelerated development of new products. Ant...

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Literature Corpus work
fdb46954-5232-5cba-ae6f-6cef54017fe4
DOI
10.22541/au.172114825.55322456/v1
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Adaptation of Aglycosylated Monoclonal Antibodies for Improved Production in Komagataella phaffiiDOI 10.22541/au.172114825.55322456/v1
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