Article

SARS-CoV-2 spike-induced syncytia are senescent and contribute to exacerbated heart failure

2022-10-11

Abstract excerpt

Patients with pre-existing heart failure are at a particularly high risk of morbidity and mortality resulting from SARS-CoV-2 infection. Direct acute cardiac injury or cytokine storms have been proposed to contribute to depressed cardiac function. However, the pathogenic mechanisms underlying the increased vulnerability to heart failure in SARS-CoV-2 infected patients are still largely unknown. Here, we found that...

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Literature Corpus work: 712a8a9c-4bde-5889-bd6c-5e1bc9fe51c9
DOI: 10.1101/2022.10.10.511541

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