Article

Mechanism of stepwise electron transfer in six-transmembrane epithelial antigen of the prostate (STEAP) 1 and 2

2021-12-23

Abstract excerpt

Six transmembrane epithelial antigen of the prostate (STEAP) is a family of membrane-embedded hemoproteins with four members, STEAP1-4, all of which have a transmembrane domain (TMD) that chelates a heme prosthetic group. STEAP2-4, but not STEAP1, have an intracellular oxidoreductase domain (OxRD) so that an electron transfer chain composed of NADPH, FAD, and heme is established to mediate electron transfer across...

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Literature Corpus work: 71282b82-b4bf-5148-9010-8772ef183dd5
DOI: 10.1101/2021.12.23.474010

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