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Article

Electron transport in cytochromes P-450 by covalent switching.

Proceedings. Biological sciences - 22 Jul 1991

Baldwin J E, Morris G M, Richards W G

Abstract excerpt

The mechanism of electron transfer in cytochrome P-450cam is presented in terms of a covalent switching mechanism. We present a model of putidaredoxin built by homology, which helps explain protein-protein interactions. The mechanism is general enough to account for the genetic variations found in the superfamily of cytochromes P-450. The detail should assist in the design of novel P-450 inhibitors and may have...

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Identifiers

PMID: 1682928
DOI: 10.1098/rspb.1991.0086

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