Article

Pan-cancer analysis identified inflamed microenvironment associated multi-omics signatures

2020-03-20

Abstract excerpt

<h4>Background</h4> Immunotherapy has revolutionized cancer therapy. However, responses are not universal. The inflamed tumor microenvironment has been reported to correlate with response in tumor patients. However, how different tumors shape their tumor microenvironment remains a critical unsolved problem. A deeper insight into the molecular characteristics of inflamed tumor microenvironment may be needed. <h4>M...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7080d65e-68f2-5886-80a0-794fd664595b
DOI: 10.1101/2020.03.17.996199

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Pan-cancer analysis identified inflamed microenvironment associated multi-omics signaturesDOI 10.1101/2020.03.17.996199Read

Analysis of genetic signatures of tumor microenvironment yields insight into mechanisms of resistance to immunotherapySemantic proximity Read

Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer types.Semantic proximity Read

Molecular correlates and therapeutic targets in T cell-inflamed versus non-T cell-inflamed tumors across cancer typesSemantic proximity Read

Intercellular Molecular Crosstalk Networks within Invasive and Immunosuppressive Tumor Microenvironment Subtypes Associated with Clinical Outcomes in Four Cancer TypesSemantic proximity Read

Distinct Tumor-TAM Interactions in IDH-Stratified Glioma Microenvironments unveiled by Single-Cell and Spatial TranscriptomicsSemantic proximity Read

Integrated Pan-Cancer Multi-Omics Analysis Reveals TMEM45A Associated with DNA Hypomethylation, Immune Exclusion, and Drug ResponseSemantic proximity Read

Applications of Single-Cell Omics to Dissect Tumor MicroenvironmentSemantic proximity Read

Comprehensive characterization of tumor microenvironment in colorectal cancer via histopathology-molecular analysisSemantic proximity Read

Pyroptosis relates to tumor microenvironment remodeling and prognosis: A pan-cancer perspectiveSemantic proximity Read

Distinct tumor-TAM interactions in IDH-stratified glioma microenvironments unveiled by single-cell and spatial transcriptomicsSemantic proximity Read

Pan-cancer tumor classification by a holistic tumor microenvironment atlasSemantic proximity Read

Pan-cancer characterization of lncRNA modifiers of immune microenvironment reveals clinically distinct de novo tumor subtypesSemantic proximity Read