Article

Integrated Pan-Cancer Multi-Omics Analysis Reveals TMEM45A Associated with DNA Hypomethylation, Immune Exclusion, and Drug Response

2026-08-14

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> : Transmembrane Protein 45A (TMEM45A) has been implicated in hypoxia tolerance and chemoresistance in several cancers; however, its molecular landscape, epigenetic regulation, and influence on the tumor immune microenvironment (TME) have not been systematically characterized across human malignancies. <bold>Methods</bold> : This study performed an integrated...

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Literature Corpus work: 82152677-8448-5d95-9705-db91b386ecaa
DOI: 10.21203/rs.3.rs-10691985/v1

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