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Pyroptosis relates to tumor microenvironment remodeling and prognosis: A pan-cancer perspective

20 Dec 2022

Abstract excerpt

Background and aim: Pyroptosis is an inflammatory form of programmed cell death implicated in inflammation and disease. Moreover, inducing pyroptosis has been appreciated as anti-cancer therapy for its ability to unleash anti-cancer immune responses. Methods: Utilizing the data available in The Cancer Genome Atlas (TCGA), pyroptosis-related genes' (PRGs) expression, genomic aberrations, and clinical significance...

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PMID: 36605187
DOI: 10.3389/fimmu.2022.1062225

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