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An in-silico study on SARS-CoV-2: Its compatibility with human tRNA pool, and the polymorphism arising in a single lineage over a month

2020-07-24

Abstract excerpt

SARS-CoV-2 has caused a global pandemic that has costed enormous human lives in the recent past. The present study is an investigation of the viral codon adaptation, ORFs’ stability and tRNA co-adaptation with humans. We observed that for the codon usage bias in viral ssRNA, ORFs have near values of folding free energies and codon adaptation index with mRNAs of the human housekeeping CDS. However, the correlation...

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Literature Corpus work
701c4dd6-6a0d-5225-8ad2-232ae7201e41
DOI
10.1101/2020.07.23.217083
Open publication

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An in-silico study on SARS-CoV-2: Its compatibility with human tRNA pool, and the polymorphism arising in a single lineage over a monthDOI 10.1101/2020.07.23.217083
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