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Article

SARS-CoV-2 has the advantage of competing the iMet-tRNAs with human hosts to allow efficient translation.

Molecular genetics and genomics : MGG - 1 Jan 2021

Wang Yan, Gai Yanhong, Li Yuefan, Li Chunxiao, Li Ziliang, Wang Xuekun

Abstract excerpt

To better understand the interaction between SARS-CoV-2 and human host and find potential ways to block the pandemic, one of the unresolved questions is that how the virus economically utilizes the resources of the hosts. Particularly, the tRNA pool has been adapted to the host genes. If the virus intends to translate its own RNA, then it has to compete with the abundant host mRNAs for the tRNA molecules....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33040198
DOI: 10.1007/s00438-020-01731-4
PMCID: PMC7547557

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