Article

Prime-boost protein subunit vaccines against SARS-CoV-2 are highly immunogenic in mice and macaques

2020-09-02

Abstract excerpt

<h4>Summary</h4> SARS-CoV-2 vaccines are advancing into human clinical trials, with emphasis on eliciting high titres of neutralising antibodies against the viral spike (S). However, the merits of broadly targeting S versus focusing antibody onto the smaller receptor binding domain (RBD) are unclear. Here we assessed prototypic S and RBD subunit vaccines in homologous or heterologous prime-boost regimens in mice...

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Literature Corpus work: 700c178a-a97b-5406-86d8-694ca9880019
DOI: 10.1101/2020.09.01.278630

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