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Article

Circulating miRNAs as diagnostic biomarkers for adolescent idiopathic scoliosis

2 Feb 2018

Abstract excerpt

The aetiology of adolescent idiopathic scoliosis (AIS) has been linked to many factors, such as asymmetric growth, neuromuscular condition, bone strength and genetic background. Recently, epigenetic factors have been proposed as contributors of AIS physiopathology, but information about the molecular mechanisms and pathways involved is scarce. Regarding epigenetic factors, microRNAs (miRNAs) are molecules that...

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PMID: 29422531
DOI: 10.1038/s41598-018-21146-x

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