Article

A Perforator-Based Adipocutaneous Skin Paddle derived from Free Muscle Flap Reconstruction: The First in-Human Model of Secondary Lymphedema

2025-10-08

Abstract excerpt

<title>Abstract</title> Secondary lymphedema remains poorly understood, particularly in terms of its pathophysiology and signaling pathways. This study aims to establish a human model for secondary Lymphedema using the perforator-based adipocutaneous skin paddle (PBASP) from vascularized free muscle flaps. The PBASP, receiving arterial and venous blood but lacking lymphatic drainage, is hypothesized to show ly...

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Literature Corpus work: 6fde1ced-6cd8-5b38-a258-5b645f59ca5b
DOI: 10.21203/rs.3.rs-7401762/v1

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