Article

Modelling and Investigating the Interactive Role of Fluid Velocity and Pore Pressure in Load-Induced Osteogenesis

2025-09-23

Abstract excerpt

Current models propose that osteogenesis occurs in regions of high mechanical stimuli such as strain, fluid velocity, or pore pressure. However, in vivo experiments on mouse tibiae under cantilever loading revealed new bone formation exclusively on the anterolateral side, despite the opposite posteromedial surface experiencing comparable magnitudes of these stimuli. This indicates that individual stimulus magnitud...

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Identifiers and source

Literature Corpus work: 6fd414de-b060-55e8-b0b1-fc6f7bf8e057
DOI: 10.1101/2025.09.22.677695

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