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Collagen type VI‑α1 and 2 repress the proliferation, migration and invasion of bladder cancer cells

7 May 2021

Abstract excerpt

The bladder cancer (BCa) microenvironment comprises heterogeneous tumor cell populations, the surrounding stroma and the extracellular matrix (ECM). Collagen, the scaffold of the tumor microenvironment, regulates ECM remodeling to promote tumor infiltration, angiogenesis, invasion and migration. The present study examined how collagen type VI‑α (COL6A) 1 and 2 function during BCa pathogenesis and progression,...

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Identifiers

PMID: 33982770
DOI: 10.3892/ijo.2021.5217

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