Article

Identification of critical cell-types using genetic modules: A case study of neurodevelopmental disorders

2023-07-04

Abstract excerpt

Identifying the critical cell-types impacted by various diseases is crucial for understanding disease mechanisms and developing targeted therapeutics. Recent advances in disease genetic module discovery and single-cell technologies provide a unique opportunity to study critical cell-types based on functional pathways and modules. Disease genetic modules are defined as sets of genes with correlated expression that...

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Literature Corpus work: 6fab3d77-782f-5df9-a00c-e2189ef972b0
DOI: 10.1101/2023.07.04.547726

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