Article

Slow Outer Hair Cell Contractions Are Essential for Fast Electrical Responses to Intense Sound

2025-04-27

Abstract excerpt

The cochlea protects itself from intense sound via slow mechanical contractions, but the real-time kinetics linking this process to the stimulus-evoked electrical potentials have remained unresolved. Here, using high-speed confocal imaging with AI-driven analysis, we synchronously measured organ of Corti mechanics and stimulus-evoked potentials in the living isolated guinea pig cochlea. We discovered an inverse ki...

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Identifiers and source

Literature Corpus work: 6f9684f3-da73-53c6-8df6-d6eed412e577
DOI: 10.1101/2025.04.24.650391

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