Article

Six years of clinical herpes simplex virus genotypic acyclovir resistance testing confirms common resistance mechanisms and identifies novel mutations

2026-06-27

Abstract excerpt

<h4>ABSTRACT</h4> Identification of acyclovir-resistant herpes simplex virus (HSV) infections is critical for directing appropriate antiviral therapy, particularly for immunocompromised patients where resistance rates can reach 30%. In 2020, the University of Washington Clinical Virology Laboratory launched the first clinical genotypic HSV drug resistance test in the United States. While genotypic testing offers...

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Literature Corpus work: 6ef17b4e-9f70-599f-bd4d-ff452477b160
DOI: 10.64898/2026.06.25.734554

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