Article
Genotypic testing improves detection of antiviral resistance in human herpes simplex virus.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Oct 2023
Glasgow Heather L, Zhu Haiying, Xie Hong, Kenkel Elizabeth J, Lee Carrie, Huang Meei-Li, Greninger Alexander L
Abstract excerpt
BACKGROUND: Antiviral resistance in human herpes simplex viruses (HSV) remains a significant clinical challenge in immunocompromised populations. Although molecular tests have largely replaced viral culture for HSV diagnosis and molecular antiviral resistance testing is available for many viruses, HSV resistance testing continues to rely on phenotypic, viral culture-based methods, requiring weeks for results....
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