Article

Benzidine Induces Proliferation of UMUC3 Bladder Cancer Cells Through Activation of ERK5 Pathway

2022-06-11

Abstract excerpt

Mounting evidences have revealed that benzidine, a known human carcinogen, is a pivotal risk factor for bladder cancer (BC). Dysregulated cell proliferation serves as a pivotal pathophysiological step in BC development. The potential mechanisms of MAPK pathways, particularly extracellular regulated protein kinases 5 (ERK5), regarding the modulation of benzidine-elicited cell proliferation are still elusive. Herein...

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Literature Corpus work: 6ebfe82b-592b-5523-9b09-e36e3e07268e
DOI: 10.1101/2022.06.11.495720

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