Article

Nasal transcriptome and epigenome analysis identifies the pathogenic features of aspirin-exacerbated respiratory disease

2022-01-23

Abstract excerpt

Background: Dysregulation of the arachidonic acid metabolic pathway is the most widely known pathomechanism of AERD. We performed integrative analysis of transcriptomic and epigenomic profiling with network analysis to determine the novel pathogenic features of AERD. <h4>Methods:</h4> Ten patients with asthma including 5 patients with AERD and another 5 patients with aspirin tolerant asthma (ATA) were enrolled. Na...

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Literature Corpus work: 6e8e2fd3-7601-533f-837c-f3a30f36a2cc
DOI: 10.22541/au.164294010.00257762/v1

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