Article

CAR-NK Cells Effectively Target the D614 and G614 SARS-CoV-2-infected Cells

2021-01-15

Abstract excerpt

<h4>ABSTRACT</h4> Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is highly contagious presenting a significant public health issue. Current therapies used to treat coronavirus disease 2019 (COVID-19) include monoclonal antibody cocktail, convalescent plasma, antivirals, immunomodulators, and anticoagulants, though the current therapeutic options remain limited and expensive. The vaccines from Pfizer...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6e57d904-e93a-56c4-8103-398664cfdc35
DOI: 10.1101/2021.01.14.426742

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

CAR-NK Cells Effectively Target the D614 and G614 SARS-CoV-2-infected CellsDOI 10.1101/2021.01.14.426742Read

CAR-NK Cells Effectively Target SARS-CoV-2-Spike-Expressing Cell Lines In VitroSemantic proximity Read

Efficacy of Targeting SARS-CoV-2 by CAR-NK CellsSemantic proximity Read

CAR-NK cell therapy: a potential antiviral platformSemantic proximity Read

TLR2/4 are novel activating receptors for SARS-CoV-2 spike protein on NK cellsSemantic proximity Read

Natural killer cell‐mediated ADCC in SARS‐CoV‐2‐infected individuals and vaccine recipientsSemantic proximity Read

NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful DevelopmentSemantic proximity Read

Peptide:MHC dependent activation of natural killer cells through KIR2DS2 generates anti-tumor responsesSemantic proximity Read

NK cells are critical for in vivo control of SARS-CoV-2 replication and suppression of lung damageSemantic proximity Read

SARS-CoV-2 Spike 1 Protein Controls Natural Killer Cell Activation via the HLA-E/NKG2A PathwaySemantic proximity Read

Activating Killer-Cell Immunoglobulin-Like Receptors Are Associated With the Severity of Coronavirus Disease 2019.Semantic proximity Read

SARS-CoV-2 modulates NK cell responses via induction of HLA-E and triggers expansion of adaptive NK cells during acute infectionSemantic proximity Read

CAR Macrophages for SARS-CoV-2 ImmunotherapySemantic proximity Read