Article

Non-cell-adhesive hydrogel promotes formation of human blastoids from primed human pluripotent stem cells

2022-06-26

Abstract excerpt

Artificial human blastoids are used to investigate early embryo development, pregnancy failures, and birth deficiencies, previously impossible without human embryos. Recent methods generating blastoids used human naive pluripotent stem cells, which are prone to genomic instability during in vitro culturing. Here, we introduce a simple, robust, and scalable method for generating human blastoids from more stable, p...

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Identifiers and source

Literature Corpus work: 6e288af8-8d8a-5f76-825f-8446b27af876
DOI: 10.1101/2022.06.23.497328

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