Article

Direct synthesis of self-organized blastocyst-like cysts derived from human pluripotent stem cells

2019-11-05

Abstract excerpt

We introduce a simple, robust and scalable method to generate self-organized blastocyst-like cysts (soBLCs) from human pluripotent stem cells (hPSCs). We use a copolymer hydrogel of poly( N -isopropylacrylamide) and poly(ethylene glycol) (PNIPAAm-PEG). hPSC aggregates with a diameter of approximately 117.2 ± 5.1 µm are cultured in a medium supplemented with a hydrogel and a serum for three days. Molecular signatu...

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Literature Corpus work: 66d24979-1b77-55c7-a439-92736d97a311
DOI: 10.1101/831487

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