Back to search

Article

Cost-Effectiveness of Genotype-Guided Acenocoumarol Therapy in Atrial Fibrillation: A Pharmacogenomic Simulation Study in the Chilean Population

2025-09-01

Abstract excerpt

<title>Abstract</title> <p> Cardiovascular diseases are the leading cause of death in Chile and worldwide. In atrial fibrillation, anticoagulation is essential, and in Chile acenocoumarol rather than warfarin, used in most countries, is the standard agent. Its dosing shows substantial interindividual variability due to <italic>CYP2C9</italic> and <italic>VKORC1</italic> polymorphisms. We developed a cohort-b...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6e217634-7413-5fda-a88c-2ae386a5810f
DOI
10.21203/rs.3.rs-7411548/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Cost-Effectiveness of Genotype-Guided Acenocoumarol Therapy in Atrial Fibrillation: A Pharmacogenomic Simulation Study in the Chilean PopulationDOI 10.21203/rs.3.rs-7411548/v1
Cost-effectiveness of genotype-guided acenocoumarol therapy in atrial fibrillation: a pharmacogenomic simulation study in the chilean population.Semantic proximity
A Pharmacogenetically Guided Acenocoumarol Dosing Algorithm for Chilean Patients: A Discovery Cohort StudySemantic proximity
Functionally Significant Coumarin-Related Variant Alleles and Time to Therapeutic Range in Chilean Cardiovascular Patients.Semantic proximity
Cost-effectiveness of genotype-guided warfarin dosing for patients with atrial fibrillation.Semantic proximity
Economic evaluation of pharmacogenomic-guided warfarin treatment for elderly Croatian atrial fibrillation patients with ischemic stroke.Semantic proximity
Cost-effectiveness of implementing a genotype-guided de-escalation strategy in patients with acute coronary syndrome.Semantic proximity
Cost-effectiveness of pharmacogenetics in anticoagulation: international differences in healthcare systems and costs.Semantic proximity
Universal versus genotype-guided use of direct oral anticoagulants in atrial fibrillation patients: a decision analysis.Semantic proximity
Pharmacogenetic-guided selection of warfarin versus novel oral anticoagulants for stroke prevention in patients with atrial fibrillation: a cost-effectiveness analysis.Semantic proximity
Cost-effectiveness of pharmacogenetic-guided dosing of phenprocoumon in atrial fibrillation.Semantic proximity
Cost-effectiveness of CYP2C19-guided antiplatelet therapy for acute coronary syndromes in Singapore.Semantic proximity
Cost-Utility Study of Warfarin Genotyping in the VACHS Affiliated Anticoagulation Clinic of Puerto Rico.Semantic proximity
Select a neighboring publication to make it the new centre.