Article
Cost-Utility Study of Warfarin Genotyping in the VACHS Affiliated Anticoagulation Clinic of Puerto Rico.
Puerto Rico health sciences journal - 1 Sept 2017
Martes-Martinez Carlos, Méndez-Sepúlveda Cristian, Millán-Molina Joel, French-Kim Matthew, Marín-Centeno Heriberto, Rivera-Miranda Giselle C, Hernández-Muñoz José J, Duconge-Soler Jorge
Abstract excerpt
OBJECTIVE: To evaluate the cost-utility of the pharmacogenetic-guided dosing of warfarin (PGx), when compared to the current dosing strategy. METHODS: A Markov model was developed to assess the impact of the genotypingguided warfarin dosing in a hypothetical cohort of patients. The model was based on the percentage of time patients spent within the therapeutic international normalized ratio (INR) range (PTTR)....
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