Article
Cost-effectiveness of pharmacogenetic-guided dosing of phenprocoumon in atrial fibrillation.
Pharmacogenomics - 1 Jun 2013
Verhoef Talitha I, Redekop William K, Veenstra David L, Thariani Rahber, Beltman Peter A, van Schie Rianne Mf, de Boer Anthonius, Maitland-van der Zee Anke-Hilse
Abstract excerpt
AIM: To investigate the cost-effectiveness of pharmacogenetic-guided phenprocoumon dosing versus standard anticoagulation care in Dutch patients with atrial fibrillation. MATERIALS & METHODS: Using a decision-analytic Markov model, cost-effectiveness of pharmacogenetic-guided therapy versus standard care was estimated. RESULTS: Compared with standard care, the pharmacogenetic-guided dosing strategy increased...
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