Functionally Significant Coumarin-Related Variant Alleles and Time to Therapeutic Range in Chilean Cardiovascular Patients.

doi:10.1177/1076029620909154

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Article

Functionally Significant Coumarin-Related Variant Alleles and Time to Therapeutic Range in Chilean Cardiovascular Patients.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Jan 2000

Rojo Mario, Roco Angela Margarita, Suarez Marcelo, Lavanderos Maria Alejandra, Verón Gabriel, Bertoglia Maria Paz, Arredondo Annabella, Nieto Elena, Rubilar Juan Carlos, Tamayo Francisca, Cruz Daniela, Muñoz Jessica, Bravo Gabriela, Salas Patricio, Mejías Fanny, Véliz Paulo, Godoy Gerald, Varela Nelson Miguel, Llull G, Quiñones Luis Abel

Abstract excerpt

Despite the development of new oral agents over the last decade, vitamin K antagonists (VKAs) remain the most widely used anticoagulants for treating and preventing thromboembolism worldwide. In Chile, the Ministry of Health indicates that acenocoumarol should be used in preference to any other coumarin. Complications of inappropriate dosing are among the most frequently reported adverse events associated with...

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PMID: 32228310
DOI: 10.1177/1076029620909154
PMCID: PMC7288841

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