Article

Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathway

2020-05-08

Abstract excerpt

<title>Abstract</title> <p>Objectives Trophoblast dysfunction during pregnancy is fundamentally involved in preeclampsia. The aim of this study was to understand how human chorionic villous mesenchymal stem cells (CV-MSCs) operate in regulation of trophoblast function.Materials and Methods We treated trophoblasts with CV-MSC supernatant under hypoxic conditions, and transcriptome and pathway analyses of trophobla...

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Literature Corpus work: 6e2114e1-b9b6-5857-b5a4-6aa02963297f
DOI: 10.21203/rs.3.rs-25663/v1

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