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Harnessing Autophagic Network Is Essential for Trophoblast Stem Cell Differentiation

7 Mar 2020

Abstract excerpt

Differentiation of trophoblast stem (TS) cells into various cell lineages of the placenta during mammalian development is accompanied by dynamic changes in its proteome for exerting the highly specialized functions of various cell subtypes. In the present study, we demonstrate that the autophagic machinery, which includes proteins for initiation, vesicle nucleation, and autophagosome maturation are robustly...

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PMID: 32143554
DOI: 10.1089/scd.2019.0296

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