Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decreased <i>STAT3</i> in human idiopathic fetal growth restriction contributes to trophoblast dysfunction

26 Feb 2015

Abstract excerpt

Abnormal trophoblast function is associated with fetal growth restriction (FGR). The JAK-STAT pathway is one of the principal signalling mechanisms by which cytokines and growth factors modulate cell proliferation, differentiation, cell migration and apoptosis. The expression of placental JAK-STAT genes in human idiopathic FGR is unknown. In this study, we propose the hypothesis that JAK-STAT pathway genes are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Pregnancy and preeclampsia studies
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25713425
DOI: 10.1530/rep-14-0622

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decreased <i>STAT3</i> in human idiopathic fetal growth restriction contributes to trophoblast dysfunctionPMID 25713425Read ↗

Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathwaySemantic proximity Read ↗

Chorionic villus-derived mesenchymal stem cell-mediated autophagy promotes proliferation and invasiveness of trophoblasts under hypoxia by activating the JAK2/STAT3 signalling pathwaySemantic proximity Read ↗

An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast DevelopmentSemantic proximity Read ↗

RNA-Seq identifies genes whose proteins are transformative in the differentiation of cytotrophoblast to syncytiotrophoblast, in human primary villous and BeWo trophoblastsSemantic proximity Read ↗

SPRY4 regulates trophoblast proliferation and apoptosis via regulating IFN‐γ‐induced STAT1 expression and activation in recurrent miscarriageSemantic proximity Read ↗

Involvement of MAPK Signalling in Human Villous Trophoblast DifferentiationSemantic proximity Read ↗

Homeobox gene transforming growth factor β-induced factor-1 (TGIF-1) is a regulator of villous trophoblast differentiation and its expression is increased in human idiopathic fetal growth restrictionSemantic proximity Read ↗

Decreased Placental FPR2 in Early Pregnancies That Later Developed Small-For-Gestation Age: A Potential Role of FPR2 in the Regulation of Epithelial-Mesenchymal TransitionSemantic proximity Read ↗

NOTCH3 signalling controls human trophoblast stem cell expansion and differentiationSemantic proximity Read ↗

NLRP7 is increased in human idiopathic fetal growth restriction and plays a critical role in trophoblast differentiationSemantic proximity Read ↗

NOTUM-mediated WNT silencing drives extravillous trophoblast cell lineage developmentSemantic proximity Read ↗

Human Trophoblast Differentiation Is Associated With Profound Gene Regulatory and Epigenetic ChangesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.