Article

Hypercapnic acidosis microenvironment promoted epithelial-to-mesenchymal transition through activating ASIC3 in lung adenocarcinoma

2022-02-08

Abstract excerpt

<h4>Background: </h4> Epithelial-mesenchymal transition (EMT) plays a major role in tumor invasion and metastasis, which is associated with poor survival in surgically resected lung cancer. Tumor microenvironment, especially extracellular acidity is a favorable factor for tumor progression and metastatic spread, and participates in EMT. However, the effects of Hypercapnic acidosis (HCA) microenvironment on EMT of...

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Literature Corpus work: 6df6403b-4a1b-52be-9a90-d8dcab992d91
DOI: 10.21203/rs.3.rs-1320137/v1

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