Article

Engineering Viral Vectors for Acoustically Targeted Gene Delivery

2021-07-27

Abstract excerpt

<h4>ABSTRACT</h4> Targeted gene delivery to the brain is a critical tool for neuroscience research and has significant potential to treat human disease. However, the site-specific delivery of common gene vectors such as adeno-associated viruses (AAVs) is typically performed via invasive injections, limiting their scope of research and clinical applications. Alternatively, focused ultrasound blood-brain-barrier op...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6de68784-6449-56b4-8a10-8442f72fc5f3
DOI: 10.1101/2021.07.26.453904

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Engineering Viral Vectors for Acoustically Targeted Gene DeliveryDOI 10.1101/2021.07.26.453904Read

Engineering viral vectors for acoustically targeted gene deliverySemantic proximity Read

Portable transcranial therapeutic ultrasound enhances targeted gene delivery for Parkinson’s disease: from rodent models to non-human primatesSemantic proximity Read

Systemic Administration of AAV9-G266A with Focused Ultrasound Enables Robust Brain Transduction with Minimal Liver Transduction.Semantic proximity Read

Focused ultrasound increases gene delivery to deep brain structure following the administration of a recombinant adeno-associated virus in the cerebrospinal fluidSemantic proximity Read

Ultrasound-Mediated Gene Therapy in Alzheimer’s Disease Validated through In Vivo PET ImagingSemantic proximity Read

Site-Specific Noninvasive Delivery of Retrograde Viral Vectors to the BrainSemantic proximity Read

Biology of adeno-associated viral vectors in the central nervous systemSemantic proximity Read

Adeno-Associated Virus Vector for Central Nervous System Gene Therapy.Semantic proximity Read

Noninvasive Control of Seizure Threshold with Acoustically Targeted ChemogeneticsSemantic proximity Read

Routes of administration for adeno-associated viruses carrying gene therapies for brain diseasesSemantic proximity Read

Noninvasive focal transgene delivery with viral neuronal tracers in the marmoset monkeySemantic proximity Read

Systemic gene delivery to the central nervous system using Adeno-associated virusSemantic proximity Read